Meningococcal Factor H–Binding Protein Variants Expressed by Epidemic Capsular Group A, W‐135, and X Strains from Africa | Zendy

Peter T. Beernink | Zendy; Dominique A. Caugant | Zendy; Jo Anne Welsch | Zendy; Oliver Koeberling | Zendy; Dan M. Granoff | Zendy

Open Access

Meningococcal Factor H–Binding Protein Variants Expressed by Epidemic Capsular Group A, W‐135, and X Strains from Africa

Author(s) -

Peter T. Beernink,

Dominique A. Caugant,

Jo Anne Welsch,

Oliver Koeberling,

Dan M. Granoff

Publication year - 2009

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/597806

Subject(s) - neisseria meningitidis , biology , bacterial outer membrane , epitope , microbiology and biotechnology , group a , antigen , group b , virology , monoclonal antibody , antibody , population , gene , bacteria , genetics , escherichia coli , medicine , demography , sociology

Meningococcal epidemics in Africa are generally caused by capsular group A strains, but W-135 or X strains also cause epidemics in this region. Factor H-binding protein (fHbp) is a novel antigen being investigated for use in group B vaccines. Little is known about fHbp in strains from other capsular groups.

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