Is the Interruption of Antiretroviral Treatment During Pregnancy an Additional Major Risk Factor for Mother‐to‐Child Transmission of HIV Type 1? | Zendy

Luisa Galli | Zendy; Donella Puliti | Zendy; Elena Chiappini | Zendy; Clara Gabiano | Zendy; G. Ferraris | Zendy; F Mig | Zendy; M Viganò | Zendy; Carlo Giaquinto | Zendy; Orazio Genovese | Zendy; Gianfranco Anzidei | Zendy; Raffaele Badolato | Zendy; Wilma Buffolano | Zendy; Anna Maccabruni | Zendy; Filippo Salvini | Zendy; Monica Cellini | Zendy; Maurizio Ruggeri | Zendy; Mariano Manzionna | Zendy; Stefania Bernardi | Zendy; PierAngelo Tovo | Zendy; Maurizio de Martino | Zendy

Open Access

Is the Interruption of Antiretroviral Treatment During Pregnancy an Additional Major Risk Factor for Mother‐to‐Child Transmission of HIV Type 1?

Author(s) -

Luisa Galli,

Donella Puliti,

Elena Chiappini,

Clara Gabiano,

G. Ferraris,

F Mig,

M Viganò,

Carlo Giaquinto,

Orazio Genovese,

Gianfranco Anzidei,

Raffaele Badolato,

Wilma Buffolano,

Anna Maccabruni,

Filippo Salvini,

Monica Cellini,

Maurizio Ruggeri,

Mariano Manzionna,

Stefania Bernardi,

PierAngelo Tovo,

Maurizio de Martino

Publication year - 2009

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/597774

Subject(s) - medicine , interquartile range , pregnancy , odds ratio , confidence interval , viral load , prospective cohort study , cohort , obstetrics , cohort study , logistic regression , confounding , gestation , pediatrics , human immunodeficiency virus (hiv) , surgery , immunology , genetics , biology

There is currently an experts' agreement discouraging interruption of antiretroviral treatment (ART) during the first trimester of pregnancy in women infected with human immunodeficiency virus type 1 (HIV-1). However, this recommendation is poorly supported by data. We evaluated the effects of discontinuing ART during pregnancy on the rate of mother-to-child transmission.

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