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There is currently an experts' agreement discouraging interruption of antiretroviral treatment (ART) during the first trimester of pregnancy in women infected with human immunodeficiency virus type 1 (HIV-1). However, this recommendation is poorly supported by data. We evaluated the effects of discontinuing ART during pregnancy on the rate of mother-to-child transmission.

Is the Interruption of Antiretroviral Treatment During Pregnancy an Additional Major Risk Factor for Mother‐to‐Child Transmission of HIV Type 1?