Open AccessMethylation Regulates Hepatitis B Viral Protein Expression
Author(s) -
Perumal Vivekanandan,
David L. Thomas,
Michael Torbenson
Publication year - 2009
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/597614
Subject(s) - cccdna , dna methylation , methylation , biology , cpg site , viral structural protein , microbiology and biotechnology , hepatitis b virus , transfection , viral protein , gene expression , virology , gene , viral replication , virus , viral entry , biochemistry , hbsag
Hepatitis B virus (HBV) DNA has been shown to contain CpG islands that are methylated in human tissue, which suggests a role for methylation in regulating viral protein production. However, data are lacking about whether methylation regulates viral gene expression.
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