Spatial Patterns in Discordant Diagnostic Test Results for Chagas Disease: Links to Transmission Hotspots | Zendy

Michael Z. Levy | Zendy; Natalie M. Bowman | Zendy; Vivian Kawai | Zendy; Joshua B. Plotkin | Zendy; Lance A. Waller | Zendy; Lilia Cabrera | Zendy; Frank Steurer | Zendy; Amy E. Seitz | Zendy; Viviana Pinedo-Cancino | Zendy; Juan G. Cornejo del Carpio | Zendy; Eleazar Córdova Benzaquen | Zendy; F. Ellis McKenzie | Zendy; James H. Maguire | Zendy; Robert H. Gilman | Zendy; Caryn Bern | Zendy

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Spatial Patterns in Discordant Diagnostic Test Results for Chagas Disease: Links to Transmission Hotspots

Author(s) -

Michael Z. Levy,

Natalie M. Bowman,

Vivian Kawai,

Joshua B. Plotkin,

Lance A. Waller,

Lilia Cabrera,

Frank Steurer,

Amy E. Seitz,

Viviana Pinedo-Cancino,

Juan G. Cornejo del Carpio,

Eleazar Córdova Benzaquen,

F. Ellis McKenzie,

James H. Maguire,

Robert H. Gilman,

Caryn Bern

Publication year - 2009

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/597464

Subject(s) - chagas disease , medicine , trypanosoma cruzi , transmission (telecommunications) , disease , immunology , pathology , parasite hosting , world wide web , computer science , electrical engineering , engineering

Diagnosis of Chagas disease is hindered by discordance between screening and confirmatory test results for Trypanosoma cruzi infection. In periurban Arequipa, Peru, spatial analysis revealed that individuals with discordant test results are spatially clustered in hotspots of T. cruzi transmission, suggesting that discordant results likely represent true infections in this setting.

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