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Attribution ofCampylobacterInfections in Northeast Scotland to Specific Sources by Use of Multilocus Sequence Typing
Author(s) -
Norval J. C. Strachan,
Fraser J. Gormley,
Ovidiu Rotariu,
I.D. Ogden,
Gordon Miller,
Geoff M. Dunn,
Samuel K. Sheppard,
John F. Dallas,
Thomas M. Reid,
H. Howie,
Martin Maiden,
Ken J. Forbes
Publication year - 2009
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/597417
Subject(s) - multilocus sequence typing , campylobacteriosis , campylobacter , biology , typing , phylogenetic tree , veterinary medicine , incidence (geometry) , genetics , genotype , medicine , bacteria , gene , physics , optics
We show that a higher incidence of campylobacteriosis is found in young children (age, <5 years) living in rural, compared with urban, areas. Association of this difference with particular animal sources was evaluated using multilocus sequence typing. This evaluation was achieved by comparing Campylobacter isolates originating from these children, retail poultry, and a range of animal sources by use of source attribution and phylogenetic analysis methods. The results indicate that chicken is a major source of infection in young urban children, although not in their rural counterparts, for which ruminant and other avian sources are more important.

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