Detection and Prediction of Active Tuberculosis Disease by a Whole‐Blood Interferon‐γ Release Assay in HIV‐1–Infected Individuals | Zendy

Maximilian C. Aichelburg | Zendy; Armin Rieger | Zendy; F Breitenecker | Zendy; Katharina GrabmeierPfistershammer | Zendy; Julia Tittes | Zendy; Stephanie Eltz | Zendy; A Aichelburg | Zendy; Georg Stingl | Zendy; Athanasios Makristathis | Zendy; Norbert Kohrgruber | Zendy

Open Access

Detection and Prediction of Active Tuberculosis Disease by a Whole‐Blood Interferon‐γ Release Assay in HIV‐1–Infected Individuals

Author(s) -

Maximilian C. Aichelburg,

Armin Rieger,

F Breitenecker,

Katharina GrabmeierPfistershammer,

Julia Tittes,

Stephanie Eltz,

A Aichelburg,

Georg Stingl,

Athanasios Makristathis,

Norbert Kohrgruber

Publication year - 2009

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/597351

Subject(s) - medicine , odds ratio , confidence interval , tuberculosis , gastroenterology , immunology , prospective cohort study , pathology

The sensitivity of whole-blood interferon-gamma release assays to detect or predict active tuberculosis in individuals infected with human immunodeficiency virus type 1 (HIV-1) has as yet not been determined. Methods. In this prospective, longitudinal, single-center study, 830 HIV-1-infected patients underwent testing with the QuantiFERON-TB Gold In-Tube (QFT-GIT) assay. Clinical screening for active tuberculosis was performed at least every 3 months for a median follow-up time of 19 months.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research