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Tuberculosis Immune Reconstitution Inflammatory Syndrome: Drug Resistance and the Critical Need for Better Diagnostics
Author(s) -
Gerald Friedland
Publication year - 2009
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/596765
Subject(s) - medicine , tuberculosis , immune reconstitution inflammatory syndrome , mycobacterium tuberculosis , drug resistance , human immunodeficiency virus (hiv) , immunology , population , intensive care medicine , extensively drug resistant tuberculosis , virology , environmental health , antiretroviral therapy , viral load , pathology , microbiology and biotechnology , biology
Tuberculosis (TB) and HIV infection are the 2 leading causes of infectious diseasesrelated mortality worldwide. An estimated one-third of the world's population (~2 billion people) are currently infected with Mycobacterium tuberculosis. In addition, 8 million new cases of active TB are estimated to occur worldwide annually, with more cases seen currently than at any time in history [1, 2]. The collision of TB and HIV infection has resulted in an estimated

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