Low-Abundance Drug-Resistant Viral Variants in Chronically HIV-Infected, Antiretroviral Treatment–Naive Patients Significantly Impact Treatment Outcomes | Zendy

Birgitte B. Simen | Zendy; Jan Fredrik Simons | Zendy; Katherine Huppler Hullsiek | Zendy; Richard M. Novak | Zendy; Rodger D. MacArthur | Zendy; John D. Baxter | Zendy; Chunli Huang | Zendy; Christine K Lubeski | Zendy; Gregory S. Turenchalk | Zendy; Michael Braverman | Zendy; Brian Desany | Zendy; Jonathan M. Rothberg | Zendy; Michael D. Miller | Zendy; Michael J. Kozal | Zendy

Open Access

Low-Abundance Drug-Resistant Viral Variants in Chronically HIV-Infected, Antiretroviral Treatment–Naive Patients Significantly Impact Treatment Outcomes

Author(s) -

Birgitte B. Simen,

Jan Fredrik Simons,

Katherine Huppler Hullsiek,

Richard M. Novak,

Rodger D. MacArthur,

John D. Baxter,

Chunli Huang,

Christine K Lubeski,

Gregory S. Turenchalk,

Michael Braverman,

Brian Desany,

Jonathan M. Rothberg,

Michael D. Miller,

Michael J. Kozal

Publication year - 2009

Publication title -

the journal of infectious diseases

Language(s) - Uncategorized

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/596736

Subject(s) - deep sequencing , resistance mutation , drug resistance , reverse transcriptase , virology , medicine , hazard ratio , lamivudine , viral load , zidovudine , regimen , confidence interval , reverse transcriptase inhibitor , biology , virus , polymerase chain reaction , antiretroviral therapy , viral disease , genetics , gene , hepatitis b virus , genome

Minor (i.e., <20% prevalence) drug-resistant human immunodeficiency virus (HIV) variants may go undetected, yet be clinically important.

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