Detection of CirculatingChlamydophila pneumoniaein Patients with Coronary Artery Disease and Healthy Control Subjects | Zendy

Sarah West | Zendy; S J Kohlhepp | Zendy; Ruyun Jin | Zendy; Curt A. Gleaves | Zendy; Walter E. Stamm | Zendy; David N. Gilbert | Zendy

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Detection of CirculatingChlamydophila pneumoniaein Patients with Coronary Artery Disease and Healthy Control Subjects

Author(s) -

Sarah West,

S J Kohlhepp,

Ruyun Jin,

Curt A. Gleaves,

Walter E. Stamm,

David N. Gilbert

Publication year - 2009

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/596710

Subject(s) - chlamydophila pneumoniae , medicine , peripheral blood mononuclear cell , chlamydia , coronary artery disease , serology , chlamydiaceae , immunology , case control study , titer , antibody , biology , biochemistry , in vitro

There is a long history of research suggesting that Chlamydophila pneumoniae is associated with coronary artery disease (CAD). C. pneumoniae in peripheral blood mononuclear cells (PBMCs) could serve as a risk factor for CAD if respiratory infection with C. pneumoniae spreads to atherosclerotic plaques through PBMCs or if infected plaques shed C. pneumoniae-laden PBMCs into the circulation.

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