Role Played by Human Mannose-Binding Lectin Polymorphisms in Pulmonary Tuberculosis | Zendy

Rosanna Capparelli | Zendy; Marco Iannaccone | Zendy; Daniela Palumbo | Zendy; Chiara Medaglia | Zendy; Emilio Moscariello | Zendy; Alfredo O. Russo | Zendy; Domenico Iannelli | Zendy

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Role Played by Human Mannose-Binding Lectin Polymorphisms in Pulmonary Tuberculosis

Author(s) -

Rosanna Capparelli,

Marco Iannaccone,

Daniela Palumbo,

Chiara Medaglia,

Emilio Moscariello,

Alfredo O. Russo,

Domenico Iannelli

Publication year - 2009

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/596658

Subject(s) - mannan binding lectin , tuberculosis , immunology , lectin pathway , sputum , complement system , lectin , odds ratio , polymerase chain reaction , biology , antibody , mannose , medicine , virology , gene , alternative complement pathway , pathology , genetics , biochemistry

Mannose-binding lectin (MBL) activates the complement system in an antibody-independent manner, enhances complement-mediated phagocytosis, and plays a major role in the regulation of inflammatory cytokine release by monocytes.

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