Hepatitis B Virus Basal Core Promoter Mutation and DNA Load Correlate with Expression of Hepatitis B Core Antigen in Patients with Chronic Hepatitis B
Author(s) -
ChunJen Liu,
YungMing Jeng,
Chi-Lin Chen,
HueiRu Cheng,
PeiJer Chen,
Ting-Chi Chen,
ChenHua Liu,
MingYang Lai,
DingShinn Chen,
JiaHorng Kao
Publication year - 2009
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/596655
Subject(s) - hbcag , hepatitis b virus , hbeag , virology , antigen , genotype , viral load , hepatitis b , hepadnaviridae , biology , virus , medicine , immunology , hbsag , gene , genetics
Expression of intrahepatic hepatitis B core antigen (HBcAg) is related to the immunopathogenesis of hepatitis B virus (HBV) infection. This study investigated the role that HBV genotype and basal core promoter (BCP) mutation play in the expression of HBcAg.
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