Resistance of Athymic Nude Mice to Experimental CutaneousBacillus anthracisInfection | Zendy

Christopher Watts | Zendy; Beth L. Hahn | Zendy; Peter G. Sohnle | Zendy

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Resistance of Athymic Nude Mice to Experimental CutaneousBacillus anthracisInfection

Author(s) -

Christopher Watts,

Beth L. Hahn,

Peter G. Sohnle

Publication year - 2009

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/596631

Subject(s) - inoculation , cyclophosphamide , bacillus anthracis , hairless , microbiology and biotechnology , ratón , biology , immunology , pathology , medicine , chemotherapy , bacteria , genetics

Previous studies in a murine cutaneous anthrax model have demonstrated that hairless and haired HRS/J mice are extremely resistant to Bacillus anthracis. Because these mice are relatively thymus deficient, we used C57BL/6 athymic nude and euthymic mice to evaluate the relationship between T cell deficiency and this heightened resistance.

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