Differential Binding of Biofilm-Derived and Suspension-GrownStaphylococcus aureusto Immobilized Platelets in Shear Flow | Zendy

Niraj Procopio Evagrio George | Zendy; Patrick YmeleLeki | Zendy; Κωνσταντίνος Κωνσταντόπουλος | Zendy; Julia Ross | Zendy

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Differential Binding of Biofilm-Derived and Suspension-GrownStaphylococcus aureusto Immobilized Platelets in Shear Flow

Author(s) -

Niraj Procopio Evagrio George,

Patrick YmeleLeki,

Κωνσταντίνος Κωνσταντόπουλος,

Julia Ross

Publication year - 2009

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/596316

Subject(s) - staphylococcus aureus , biofilm , platelet , microbiology and biotechnology , adhesion , suspension (topology) , chemistry , bacteria , biology , immunology , genetics , organic chemistry , mathematics , homotopy , pure mathematics

The adhesion of Staphylococcus aureus to platelets is a critical first step in endovascular infection. S. aureus is known to form biofilms and detached cells are likely responsible for initiating bloodborne secondary infections. Although several previous studies have evaluated the mechanisms of S. aureus-platelet binding, standard procedures have used suspension-grown cells, which are known to differ in their adhesion properties from biofilm-derived cells.

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