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The adhesion of Staphylococcus aureus to platelets is a critical first step in endovascular infection. S. aureus is known to form biofilms and detached cells are likely responsible for initiating bloodborne secondary infections. Although several previous studies have evaluated the mechanisms of S. aureus-platelet binding, standard procedures have used suspension-grown cells, which are known to differ in their adhesion properties from biofilm-derived cells.

Differential Binding of Biofilm-Derived and Suspension-GrownStaphylococcus aureusto Immobilized Platelets in Shear Flow