Use of T Cell–Based Diagnosis of Tuberculosis Infection to Optimize Interpretation of Tuberculin Skin Testing for Child Tuberculosis Contacts | Zendy

Mustafa Bakır | Zendy; Davinder Dosanjh | Zendy; Jonathan J Deeks | Zendy; Ahmet Soysal | Zendy; Kerry Millington | Zendy; Serpil Efe | Zendy; Yasemin Aslan | Zendy; Dilek Polat | Zendy; Nihat Kodallı | Zendy; Ayşegül Yağcı | Zendy; Işıl Barlan | Zendy; Nerin N. Bahçeciler | Zendy; Emel Ekşioğlu | Zendy; Ajit Lalvani | Zendy

Open Access

Use of T Cell–Based Diagnosis of Tuberculosis Infection to Optimize Interpretation of Tuberculin Skin Testing for Child Tuberculosis Contacts

Author(s) -

Mustafa Bakır,

Davinder Dosanjh,

Jonathan J Deeks,

Ahmet Soysal,

Kerry Millington,

Serpil Efe,

Yasemin Aslan,

Dilek Polat,

Nihat Kodallı,

Ayşegül Yağcı,

Işıl Barlan,

Nerin N. Bahçeciler,

Emel Ekşioğlu,

Ajit Lalvani

Publication year - 2009

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/595847

Subject(s) - medicine , tuberculin , tuberculosis , vaccination , cutoff , tuberculosis diagnosis , receiver operating characteristic , immunology , skin test , bcg vaccine , pediatrics , mycobacterium tuberculosis , pathology , physics , quantum mechanics

Treatment of recent tuberculosis infection in children aged <2 years is essential, because of high risk of progression to disease, but diagnosis is hindered by the inaccuracy of the tuberculin skin test (TST). More-accurate T cell-based tests of infection could enhance diagnosis by optimizing interpretation of the TST results.

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