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Contribution of Immunological and Virological Factors to Extremely Severe Primary HIV Type 1 Infection
Author(s) -
Judith Dalmau,
María C. Puertas,
Marta Azuara,
Ana Mariño,
Nicole Frahm,
Beatriz Mothe,
Nuria IzquierdoUseros,
María J. Buzón,
Roger Paredes,
Lourdes Matas,
Todd M. Allen,
Christian Brander,
Carlos Rodrigo,
Bonaventura Clotet,
Javier MartínezPicado
Publication year - 2008
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/595704
Subject(s) - tropism , virology , immunology , human leukocyte antigen , virus , hiv antigens , immune system , medicine , cytotoxic t cell , transmission (telecommunications) , lentivirus , biology , viral load , viral disease , antigen , genetics , electrical engineering , in vitro , engineering
During acute human immunodeficiency virus (HIV) infection, high viral loads and the induction of host immune responses typically coincide with the onset of clinical symptoms. However, clinically severe presentations during acute HIV type 1 (HIV-1) infection, including AIDS-defining symptoms, are unusual.

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