Broad Cross-Protection against H5N1 Avian Influenza Virus Infection by Means of Monoclonal Antibodies that Map to Conserved Viral Epitopes | Zendy

Yixin Chen | Zendy; Kun Qin | Zendy; Wai Lan Wu | Zendy; Guoqiang Li | Zendy; Jun Zhang | Zendy; Hailian Du | Zendy; Mun Hon Ng | Zendy; J. WaiKuo Shih | Zendy; Malik Peiris | Zendy; Yi Guan | Zendy; Honglin Chen | Zendy; Ningshao Xia | Zendy

Open Access

Broad Cross-Protection against H5N1 Avian Influenza Virus Infection by Means of Monoclonal Antibodies that Map to Conserved Viral Epitopes

Author(s) -

Yixin Chen,

Kun Qin,

Wai Lan Wu,

Guoqiang Li,

Jun Zhang,

Hailian Du,

Mun Hon Ng,

J. WaiKuo Shih,

Malik Peiris,

Yi Guan,

Honglin Chen,

Ningshao Xia

Publication year - 2008

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/594374

Subject(s) - virology , influenza a virus subtype h5n1 , hemagglutinin (influenza) , monoclonal antibody , biology , epitope , virus , antigenic drift , h5n1 genetic structure , influenza a virus , neutralization , antibody , microbiology and biotechnology , immunology , medicine , covid-19 , infectious disease (medical specialty) , disease , pathology

Passive immunization with human H5 antisera or H5-specific monoclonal antibodies (MAbs) has potential as an effective treatment for acute H5N1 influenza virus infection, but its efficacy against antigenically diverse H5N1 viruses is unconfirmed.

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