Myeloid Differentiation Primary Response Gene 88 Is Required for the Resolution of Otitis Media | Zendy

Michelle Hernández | Zendy; Anke Leichtle | Zendy; Kwang Pak | Zendy; J. Ebmeyer | Zendy; Sara Euteneuer | Zendy; Marygorret Obonyo | Zendy; Donald G. Guiney | Zendy; Nicholas J. Webster | Zendy; David H. Broide | Zendy; Allen F. Ryan | Zendy; Stephen I. Wasserman | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Myeloid Differentiation Primary Response Gene 88 Is Required for the Resolution of Otitis Media

Author(s) -

Michelle Hernández,

Anke Leichtle,

Kwang Pak,

J. Ebmeyer,

Sara Euteneuer,

Marygorret Obonyo,

Donald G. Guiney,

Nicholas J. Webster,

David H. Broide,

Allen F. Ryan,

Stephen I. Wasserman

Publication year - 2008

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/593213

Subject(s) - inflammation , immunology , otitis , haemophilus influenzae , receptor , myeloid , biology , medicine , microbiology and biotechnology , biochemistry , antibiotics , genetics

Signaling defects in the Toll-like receptor (TLR) pathway, such as interleukin-1 receptor-associated kinase 4 deficiency, highlight the prominence of TLR signaling in the defense against bacterial disease. Because myeloid differentiation primary response gene 88 (MyD88) can transduce signals from almost all TLRs, we studied its role in otitis media (OM), the most common upper respiratory tract bacterial infectious disease in young children.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research