Genetic Relationships between Respiratory Pathogens Isolated from Dental Plaque and Bronchoalveolar Lavage Fluid from Patients in the Intensive Care Unit Undergoing Mechanical Ventilation | Zendy

SeokMo Heo | Zendy; Elaine M. Haase | Zendy; Alan J. Lesse | Zendy; Steven R. Gill | Zendy; Frank A. Scannapieco | Zendy

Open Access

Genetic Relationships between Respiratory Pathogens Isolated from Dental Plaque and Bronchoalveolar Lavage Fluid from Patients in the Intensive Care Unit Undergoing Mechanical Ventilation

Author(s) -

SeokMo Heo,

Elaine M. Haase,

Alan J. Lesse,

Steven R. Gill,

Frank A. Scannapieco

Publication year - 2008

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/593193

Subject(s) - bronchoalveolar lavage , ventilator associated pneumonia , medicine , mechanical ventilation , intensive care unit , pneumonia , respiratory system , intensive care , intensive care medicine , dental plaque , lung , dentistry

Ventilator-associated pneumonia (VAP) is a leading cause of morbidity and mortality in patients hospitalized in intensive care units. Recent studies suggest that dental plaque biofilms serve as a reservoir for respiratory pathogens. The goal of this study was to determine the genetic relationship between strains of respiratory pathogens first isolated from the oral cavity and later isolated from bronchoalveolar lavage fluid from the same patient undergoing mechanical ventilation with suspected VAP.

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