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Sequence Variation in Group AStreptococcusPili and Association of Pilus Backbone Types with Lancefield T Serotypes
Author(s) -
Fabiana Falugi,
Chiara Zingaretti,
Vittoria Pinto,
Massimo A. Mariani,
Laura Amodeo,
Andrea G. O. Manetti,
Sabrina Capo,
James M. Musser,
Graziella Orefici,
Immaculada Margarit,
John L. Telford,
Guido Grandi,
Marirosa Mora
Publication year - 2008
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/593176
Subject(s) - pilus , serotype , microbiology and biotechnology , streptococcus , biology , genetics , bacteria , gene , escherichia coli
We previously reported that group A Streptococcus (GAS) pili are the T antigens described by Rebecca Lancefield. We also showed that these pili, constituted by backbone, ancillary 1, and ancillary 2 proteins, confer protection against GAS challenge in a mouse model.

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