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Low mannan-binding lectin (MBL) levels, caused by MBL2 polymorphisms, are suggested to contribute to susceptibility to respiratory tract infections (RTIs), particularly early in life. Large-scale replication of previous associations is needed, however. We investigated the association between MBL2 polymorphisms and the frequency of RTI in a large population-based birth cohort of white children.

Polymorphisms in the Mannan‐Binding Lectin Gene Are Not Associated with Questionnaire‐Reported Respiratory Tract Infections in Children