Recovery of Viremic Control after Superinfection with Pathogenic HIV Type 1 in a Long‐Term Elite Controller of HIV Type 1 Infection | Zendy

Andrea Rachinger | Zendy; Marjon Navis | Zendy; Sander van Assen | Zendy; P. H. P. Groeneveld | Zendy; Hanneke Schuitemaker | Zendy

Open Access

Recovery of Viremic Control after Superinfection with Pathogenic HIV Type 1 in a Long‐Term Elite Controller of HIV Type 1 Infection

Author(s) -

Andrea Rachinger,

Marjon Navis,

Sander van Assen,

P. H. P. Groeneveld,

Hanneke Schuitemaker

Publication year - 2008

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/592978

Subject(s) - superinfection , virology , medicine , viral load , human immunodeficiency virus (hiv) , viral replication , immunology , viral disease , virus

A human immunodeficiency virus type 1 (HIV-1)-infected elite controller (defined as an untreated HIV-1-infected person with a plasma HIV-1 RNA level <50 copies/mL for at least 12 months) who experienced a viremic episode after superinfection regained natural viremic control, although the viral loads in the patient's 2 partners, infected with the same viral strain, were continuously approximately 30-fold higher. Thus, host mechanisms seem to be able to repeatedly control HIV-1 replication, halting disease progression.

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