Immunocompromised Hosts: Cryptococcosis in Solid Organ Transplant Recipients: Current State of the Science | Zendy

Nina Singh | Zendy; Françoise Dromer | Zendy; John R. Perfect | Zendy; Olivier Lortholary | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Immunocompromised Hosts: Cryptococcosis in Solid Organ Transplant Recipients: Current State of the Science

Author(s) -

Nina Singh,

Françoise Dromer,

John R. Perfect,

Olivier Lortholary

Publication year - 2008

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/592690

Subject(s) - cryptococcosis , immunosuppression , medicine , calcineurin , immunology , disease , opportunistic infection , antifungal , organ transplantation , intensive care medicine , immune system , immune reconstitution inflammatory syndrome , transplantation , human immunodeficiency virus (hiv) , dermatology , viral disease , antiretroviral therapy , viral load

Cryptococcosis remains a significant opportunistic infection in solid organ transplant recipients. Disease presentation and outcomes may be affected by, among other factors, the use of calcineurin inhibitor immunosuppressive agents. It is being increasingly recognized that rapid reversal of immunosuppression in transplant recipients treated for cryptococcosis incurs the risk of immune reconstitution inflammatory syndrome, which resembles worsening disease or relapse. This review summarizes the current state of knowledge regarding cryptococcosis in transplant recipients and highlights areas where future investigations are needed to further optimize outcomes for these patients.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research