Broad Immunogenicity of a Multigene, Multiclade HIV‐1 DNA Vaccine Boosted with Heterologous HIV‐1 Recombinant Modified Vaccinia Virus Ankara | Zendy

Eric Sandström | Zendy; Charlotta Nilsson | Zendy; Bo Hejdeman | Zendy; Andreas Bråve | Zendy; Göran Bratt | Zendy; Merlin L. Robb | Zendy; Josephine H. Cox | Zendy; Thomas C. VanCott | Zendy; Mary Marovich | Zendy; Richard Stout | Zendy; Said Aboud | Zendy; Muhammad Bakari | Zendy; Kisali Pallangyo | Zendy; Karl Ljungberg | Zendy; Bernard Moss | Zendy; Patricia L. Earl | Zendy; Nelson L. Michael | Zendy; Deborah L. Birx | Zendy; Fred Mhalu | Zendy; Britta Wahrén | Zendy; Gunnel Biberfeld | Zendy

Open Access

Broad Immunogenicity of a Multigene, Multiclade HIV‐1 DNA Vaccine Boosted with Heterologous HIV‐1 Recombinant Modified Vaccinia Virus Ankara

Author(s) -

Eric Sandström,

Charlotta Nilsson,

Bo Hejdeman,

Andreas Bråve,

Göran Bratt,

Merlin L. Robb,

Josephine H. Cox,

Thomas C. VanCott,

Mary Marovich,

Richard Stout,

Said Aboud,

Muhammad Bakari,

Kisali Pallangyo,

Karl Ljungberg,

Bernard Moss,

Patricia L. Earl,

Nelson L. Michael,

Deborah L. Birx,

Fred Mhalu,

Britta Wahrén,

Gunnel Biberfeld

Publication year - 2008

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/592507

Subject(s) - immunogenicity , virology , vaccinia , modified vaccinia ankara , poxviridae , heterologous , dna vaccination , virus , hiv vaccine , orthopoxvirus , biology , duck embryo vaccine , aids vaccines , medicine , recombinant dna , human immunodeficiency virus (hiv) , vaccine trial , immunology , antibody , immunization , gene , genetics , rabies virus

A human immunodeficiency virus (HIV) vaccine that limits disease and transmission is urgently needed. This clinical trial evaluated the safety and immunogenicity of an HIV vaccine that combines a plasmid-DNA priming vaccine and a modified vaccinia virus Ankara (MVA) boosting vaccine.

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