Murine Model to Study the Invasion and Survival ofMycobacterium tuberculosisin the Central Nervous System | Zendy

Nicholas A. Be | Zendy; Gyanu Lamichhane | Zendy; J Grosset | Zendy; Sandeep Tyagi | Zendy; Qijian Cheng | Zendy; Kwang Sik Kim | Zendy; William R. Bishai | Zendy; Sanjay K. Jain | Zendy

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Murine Model to Study the Invasion and Survival ofMycobacterium tuberculosisin the Central Nervous System

Author(s) -

Nicholas A. Be,

Gyanu Lamichhane,

J Grosset,

Sandeep Tyagi,

Qijian Cheng,

Kwang Sik Kim,

William R. Bishai,

Sanjay K. Jain

Publication year - 2008

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/592447

Subject(s) - tuberculosis , mycobacterium tuberculosis , immunology , biology , immune system , pathogenesis , lung , central nervous system , pathology , microbiology and biotechnology , medicine , neuroscience

Tuberculosis of the central nervous system (CNS) is a serious, often fatal disease primarily affecting young children. It develops after hematogenous dissemination and subsequent invasion of the CNS by Mycobacterium tuberculosis. The microbial determinants involved in CNS disease are poorly characterized.

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