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Drug Toxicity, HIV Progression, or Comorbidity of Aging: Does Tipranavir Use Increase the Risk of Intracranial Hemorrhage?
Author(s) -
Amy C. Justice,
David S. Zingmond,
Kirsha S. Gordon,
Shawn L. Fultz,
Joseph L. Goulet,
Joseph T. King,
Dawn M. Bravata,
Hernán Valdez,
Michael D. Kraft,
Kristin Mattocks
Publication year - 2008
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/592302
Subject(s) - medicine , comorbidity , food and drug administration , toxicity , drug , pharmacology
The US Food and Drug Administration has issued a warning that tipranavir may be associated with increased risk of intracranial hemorrhage. We studied 2 large cohorts to estimate the background rate of intracranial hemorrhage and compared it with rates reported among persons who had been exposed to tipranavir.

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