Safety and Immunogenicity of an Inactivated Influenza A/H5N1 Vaccine Given with or without Aluminum Hydroxide to Healthy Adults: Results of a Phase I–II Randomized Clinical Trial
Author(s) -
Wendy A. Keitel,
James Campbell,
John J. Treanor,
Emmanuel B. Walter,
Shital M. Patel,
Fenhua He,
Diana L. Noah,
Heather Hill
Publication year - 2008
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/592172
Subject(s) - immunogenicity , influenza a virus subtype h5n1 , virology , medicine , influenza vaccine , phase (matter) , clinical trial , randomized controlled trial , hydroxide , microbiology and biotechnology , immunology , vaccination , biology , antibody , chemistry , virus , organic chemistry
Dose-sparing strategies are being explored for vaccines against pandemic influenza. We evaluated the dose-sparing potential of aluminum hydroxide (AlOH) adjuvant.
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