Preferential Protection ofBorrelia burgdorferiSensu Stricto by a Salp15 Homologue inIxodes ricinusSaliva | Zendy

Joppe W. Hovius | Zendy; Tim J. Schuijt | Zendy; Karel de Groot | Zendy; Joris J. T. H. Roelofs | Zendy; G. Anneke Oei | Zendy; J. Arnoud Marquart | Zendy; Regina de Beer | Zendy; Cornelis van ‘t Veer | Zendy; Tom van der Poll | Zendy; Nandhini Ramamoorthi | Zendy; Erol Fikrig | Zendy; Alje P. van Dam | Zendy

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Preferential Protection ofBorrelia burgdorferiSensu Stricto by a Salp15 Homologue inIxodes ricinusSaliva

Author(s) -

Joppe W. Hovius,

Tim J. Schuijt,

Karel de Groot,

Joris J. T. H. Roelofs,

G. Anneke Oei,

J. Arnoud Marquart,

Regina de Beer,

Cornelis van ‘t Veer,

Tom van der Poll,

Nandhini Ramamoorthi,

Erol Fikrig,

Alje P. van Dam

Publication year - 2008

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/591917

Subject(s) - borrelia burgdorferi , borrelia afzelii , ixodes scapularis , borrelia garinii , biology , borrelia , microbiology and biotechnology , ixodes ricinus , ixodes , virology , ricinus , antibody , lyme disease , tick , immunology , botany

Ixodes ticks are the main vectors for Borrelia burgdorferi sensu lato. In the United States, B. burgdorferi is the sole causative agent of Lyme borreliosis and is transmitted by Ixodes scapularis. In Europe, 3 Borrelia species-B. burgdorferi, B. garinii, and B. afzelii-are prevalent, which are transmitted by Ixodes ricinus. The I. scapularis salivary protein Salp15 has been shown to bind to B. burgdorferi outer surface protein (Osp) C, protecting the spirochete from antibody-mediated killing.

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