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The Impact of Antimicrobial‐Resistant, Health Care–Associated Infections on Mortality in the United States
Author(s) -
R. Monina Klevens,
Jonathan R. Edwards,
R. P. Gaynes
Publication year - 2008
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/591698
Subject(s) - medicine , antimicrobial , pseudomonas aeruginosa , staphylococcus aureus , pneumonia , intensive care medicine , microbiology and biotechnology , bacteria , biology , genetics
We used data reported from US hospitals to the National Nosocomial Infection Surveillance System of the Centers for Disease Control and Prevention for 3 specific infections: Staphylococcus aureus bloodstream infections, Pseudomonas aeruginosa pneumonias, and Escherichia coli urinary tract infections. We evaluated the proportion of infections with antimicrobial-resistant isolates and the relative risk of death associated with the resistant pathogen in the period 2000-2004, compared with the period 1990-1994. The proportion of antimicrobial-resistant infections increased, but there was no change in the relative risk of death between the 2 periods.

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