Open AccessInnate Immunity to Pneumococcal Infection of the Central Nervous System Depends on Toll‐Like Receptor (TLR) 2 and TLR4
Author(s) -
Matthias Klein,
Bianca Obermaier,
Barbara Angele,
HansWalter Pfister,
Hermann Wagner,
Uwe Koedel,
Carsten J. Kirschning
Publication year - 2008
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/591626
Subject(s) - tlr2 , immunology , toll like receptor , biology , immune system , tlr4 , innate immune system , microglia , acquired immune system , inflammation
Recent studies have suggested that, in addition to Toll-like receptor (TLR) 2, other pattern recognition receptors mediate activation of the immune response after infection of the central nervous system (CNS) with Streptococcus pneumoniae (SP).
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