Analysis of Nevirapine (NVP) Resistance in Ugandan Infants Who Were HIV Infected Despite Receiving Single-Dose (SD) NVP versus SD NVP Plus Daily NVP Up to 6 Weeks of Age to Prevent HIV Vertical Transmission | Zendy

Jessica D. Church | Zendy; Saad B. Omer | Zendy; Laura Guay | Zendy; Wei Huang | Zendy; Jessica Lidström | Zendy; Philippa Musoke | Zendy; Francis Mmiro | Zendy; J. Brooks Jackson | Zendy; Susan H. Eshleman | Zendy

Open Access

Analysis of Nevirapine (NVP) Resistance in Ugandan Infants Who Were HIV Infected Despite Receiving Single-Dose (SD) NVP versus SD NVP Plus Daily NVP Up to 6 Weeks of Age to Prevent HIV Vertical Transmission

Author(s) -

Jessica D. Church,

Saad B. Omer,

Laura Guay,

Wei Huang,

Jessica Lidström,

Philippa Musoke,

Francis Mmiro,

J. Brooks Jackson,

Susan H. Eshleman

Publication year - 2008

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/591503

Subject(s) - nevirapine , medicine , breastfeeding , human immunodeficiency virus (hiv) , virology , genotyping , drug resistance , immunology , pediatrics , biology , viral load , antiretroviral therapy , genotype , microbiology and biotechnology , biochemistry , gene

Single-dose nevirapine (SD NVP) at birth plus NVP prophylaxis for the infant up to 6 weeks of age is superior to SD NVP alone for prevention of vertical transmission of human immunodeficiency virus (HIV) through breastfeeding. We analyzed NVP resistance in HIV-infected Ugandan infants who received either SD NVP or extended NVP prophylaxis.

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