Cholera Toxin–Specific Memory B Cell Responses Are Induced in Patients with Dehydrating Diarrhea Caused byVibrio choleraeO1
Author(s) -
Channa R. Jayasekera,
Jason B. Harris,
Md Saruar Bhuiyan,
Fahima Chowdhury,
Ashraful Islam Khan,
A. S. G. Faruque,
Regina C. LaRocque,
Edward T. Ryan,
Rafi Ahmed,
Firdausi Qadri,
Stephen B. Calderwood
Publication year - 2008
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/591500
Subject(s) - vibrio cholerae , cholera toxin , cholera , immune system , diarrhea , microbiology and biotechnology , immunology , immunity , antibody , humoral immunity , biology , antigen , vibrionaceae , intestinal mucosa , toxin , enterotoxin , virology , medicine , bacteria , escherichia coli , pathology , genetics , biochemistry , gene
Infection with Vibrio cholerae induces durable immunity against subsequent disease, a process hypothesized to reflect anamnestic immune responses at the intestinal mucosa. The presence of antigen-specific memory B cells may therefore be a more direct measure of protection than serum antibody responses.
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