Association of EnterotoxigenicBacteroides fragilisInfection with Inflammatory Diarrhea | Zendy

Cynthia L. Sears | Zendy; Salequl Islam | Zendy; Amit Saha | Zendy; Maleka Arjumand | Zendy; Nur Alam | Zendy; Shah M. Faruque | Zendy; Mohammed Abdus Salam | Zendy; Jai W. Shin | Zendy; David W. Hecht | Zendy; Andrej Weintraub | Zendy; R. Bradley Sack | Zendy; Firdausi Qadri | Zendy

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Association of EnterotoxigenicBacteroides fragilisInfection with Inflammatory Diarrhea

Author(s) -

Cynthia L. Sears,

Salequl Islam,

Amit Saha,

Maleka Arjumand,

Nur Alam,

Shah M. Faruque,

Mohammed Abdus Salam,

Jai W. Shin,

David W. Hecht,

Andrej Weintraub,

R. Bradley Sack,

Firdausi Qadri

Publication year - 2008

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/591130

Subject(s) - medicine , diarrhea , bacteroides fragilis , immunology , proinflammatory cytokine , abdominal pain , irritable bowel syndrome , disease , inflammatory bowel disease , inflammation , antibiotics , microbiology and biotechnology , biology

Diarrheal illnesses remain a leading cause of morbidity and mortality globally, with increasing recognition of long-term sequelae, including postinfectious irritable bowel syndrome and growth faltering, as well as cognitive deficits in children. Identification of specific etiologic agents is often lacking. In vitro and in vivo data suggest that enterotoxigenic Bacteroides fragilis (ETBF) may contribute to the burden of colonic inflammatory diarrheal disease. The study goal was to investigate the pathogenesis of ETBF diarrheal illnesses.

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