Emergence of Drug Resistance in HIV Type 1–Infected Patients after Receipt of First‐Line Highly Active Antiretroviral Therapy: A Systematic Review of Clinical Trials | Zendy

Ravindra K. Gupta | Zendy; Andrew Hill | Zendy; Anthony Sawyer | Zendy; Deenan Pillay | Zendy

Open Access

Emergence of Drug Resistance in HIV Type 1–Infected Patients after Receipt of First‐Line Highly Active Antiretroviral Therapy: A Systematic Review of Clinical Trials

Author(s) -

Ravindra K. Gupta,

Andrew Hill,

Anthony Sawyer,

Deenan Pillay

Publication year - 2008

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/590943

Subject(s) - medicine , lamivudine , resistance mutation , abacavir , reverse transcriptase inhibitor , drug resistance , confidence interval , stavudine , zidovudine , hiv drug resistance , reverse transcriptase , viral load , virology , antiretroviral therapy , human immunodeficiency virus (hiv) , biology , virus , viral disease , polymerase chain reaction , hepatitis b virus , biochemistry , microbiology and biotechnology , gene

Resistance to antiretroviral combination therapy is associated with increased mortality. Understanding the relative risks of emerging resistance to first-line therapy is of importance for both resource-rich and resource-poor settings.

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