Initial Human Herpesvirus–8 Rash and Multicentric Castleman Disease | Zendy

Benjamin Wyplosz | Zendy; A. Carlotti | Zendy; L. Escaut | Zendy; Nicolas Vignier | Zendy; Catherine Guettier | Zendy; F. Agbalika | Zendy; Daniel Vittecoq | Zendy; N. Dupin | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Initial Human Herpesvirus–8 Rash and Multicentric Castleman Disease

Author(s) -

Benjamin Wyplosz,

A. Carlotti,

L. Escaut,

Nicolas Vignier,

Catherine Guettier,

F. Agbalika,

Daniel Vittecoq,

N. Dupin

Publication year - 2008

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/590942

Subject(s) - rash , medicine , human herpesvirus 6 , human herpesvirus , lytic cycle , disease , virology , immunology , human immunodeficiency virus (hiv) , virus , biopsy , castleman disease , pathology , viral disease , dermatology , herpesviridae

We describe a human immunodeficiency virus-infected man with relapsing rashes and reactivation of human herpesvirus-8 (HHV-8) infection, which evolved into multicentric Castleman disease. Initial skin biopsy revealed infiltrating HHV-8-positive plasmablasts, a subset of which supported lytic infection. We document the first case, to our knowledge, of HHV-8-induced rash and suggest that circulating plasmablasts drive HHV-8 to target tissues.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research