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An Adjuvanted, Low‐Dose, Pandemic Influenza A (H5N1) Vaccine Candidate Is Safe, Immunogenic, and Induces Cross‐Reactive Immune Responses in Healthy Adults
Author(s) -
Karin Levie,
Isabel LerouxRoels,
Karel Hoppenbrouwers,
AnneDiane Kervyn,
Corinne Vandermeulen,
Sheron Forgus,
G LEROUXROELS,
Sylvie Pichon,
Inca Kusters
Publication year - 2008
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/590913
Subject(s) - adjuvant , medicine , vaccination , influenza vaccine , hemagglutinin (influenza) , hemagglutination assay , immunology , trivalent influenza vaccine , population , antibody titer , adverse effect , virology , antigen , antibody , titer , environmental health
To protect a naive global population against pandemic influenza, pandemic vaccines should be effective at low antigen doses, because of limited manufacturing capacity.

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