Liposome Delivery ofChlamydia muridarumMajor Outer Membrane Protein Primes a Th1 Response That Protects against Genital Chlamydial Infection in a Mouse Model1 | Zendy

Jon Hansen | Zendy; Klaus T. Jensen | Zendy; Frank Follmann | Zendy; Else Marie Agger | Zendy; Michael Theisen | Zendy; Peter Andersen | Zendy

Open Access

Liposome Delivery ofChlamydia muridarumMajor Outer Membrane Protein Primes a Th1 Response That Protects against Genital Chlamydial Infection in a Mouse Model1

Author(s) -

Jon Hansen,

Klaus T. Jensen,

Frank Follmann,

Else Marie Agger,

Michael Theisen,

Peter Andersen

Publication year - 2008

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/590670

Subject(s) - chlamydia , virology , chlamydiaceae , biology , liposome , sex organ , immunology , chlamydia trachomatis , genetics , biochemistry

Immunity to chlamydia is thought to rely on interferon (IFN)-gamma-secreting T helper cells type 1 (Th1) with an additional effect of secreted antibodies. A need for Th1-polarizing adjuvants in experimental chlamydia vaccines has been demonstrated, and antigen conformation has also been reported as being important for raising protective immunity.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research