Variants in the Toll‐Like Receptor Signaling Pathway and Clinical Outcomes of Malaria | Zendy

Fabiana M. S. Leoratti | Zendy; Lilian Farias | Zendy; Fabiana Alves | Zendy; Martha Cecília Suárez-Mútis | Zendy; José Rodrigues Coura | Zendy; Jorge Kalil | Zendy; Erney P. Camargo | Zendy; Sandra Lúcia de Moraes | Zendy; Rajendranath Ramasawmy | Zendy

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Variants in the Toll‐Like Receptor Signaling Pathway and Clinical Outcomes of Malaria

Author(s) -

Fabiana M. S. Leoratti,

Lilian Farias,

Fabiana Alves,

Martha Cecília Suárez-Mútis,

José Rodrigues Coura,

Jorge Kalil,

Erney P. Camargo,

Sandra Lúcia de Moraes,

Rajendranath Ramasawmy

Publication year - 2008

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/590440

Subject(s) - malaria , plasmodium falciparum , odds ratio , immunology , parasitemia , single nucleotide polymorphism , genotype , allele , biology , asymptomatic , allele frequency , medicine , virology , genetics , gene

Malaria is one of the most significant infectious diseases in the world and is responsible for a large proportion of infant deaths. Toll-like receptors (TLRs), key components of innate immunity, are central to countering infection. Variants in the TLR-signaling pathway are associated with susceptibility to infectious diseases.

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