Distinct Outcomes ofTrypanosoma cruziInfection in Hamsters Are Related to Myocardial Parasitism, Cytokine/Chemokine Gene Expression, and Protein Expression Profile
Author(s) -
Angelina M. Bilate,
Priscila Camillo Teixeira,
Susan Pereira Ribeiro,
Thales de Brito,
Ana Maria Gonçalves da Silva,
Momtchilo Russo,
Jorge Kalil,
Edécio CunhaNeto
Publication year - 2008
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/590347
Subject(s) - trypanosoma cruzi , biology , chagas disease , myocarditis , chemokine , immunology , parasitemia , cytokine , mesocricetus , microbiology and biotechnology , virology , hamster , inflammation , medicine , world wide web , computer science , plasmodium falciparum , malaria , parasite hosting
Trypanosoma cruzi-infected outbred hamsters reproduce the range of different outcomes of Chagas disease noted in humans. We tested whether myocarditis, its mediators, and myocardial protein expression are related to the severity of the acute phase of T. cruzi infection in the hamster model.
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