Low Serum Mannose‐Binding Lectin Level Increases the Risk of Death due to Pneumococcal Infection | Zendy

Damon P. Eisen | Zendy; Melinda M. Dean | Zendy; Marja A. Boermeester | Zendy; Katy Fidler | Zendy; Anthony Gordon | Zendy; Gitte Kronborg | Zendy; Jürgen F. J. Kun | Zendy; YL Lau | Zendy; Antoni Payeras | Zendy; Helgi Valdimarsson | Zendy; Stephen J. Brett | Zendy; WaiKi Ip | Zendy; Joan Milà | Zendy; Mark Peters | Zendy; Saedís Saevarsdóttir | Zendy; J. W. Oliver van Till | Zendy; Charles Hinds | Zendy; Emma S. McBryde | Zendy

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Low Serum Mannose‐Binding Lectin Level Increases the Risk of Death due to Pneumococcal Infection

Author(s) -

Damon P. Eisen,

Melinda M. Dean,

Marja A. Boermeester,

Katy Fidler,

Anthony Gordon,

Gitte Kronborg,

Jürgen F. J. Kun,

YL Lau,

Antoni Payeras,

Helgi Valdimarsson,

Stephen J. Brett,

WaiKi Ip,

Joan Milà,

Mark Peters,

Saedís Saevarsdóttir,

J. W. Oliver van Till,

Charles Hinds,

Emma S. McBryde

Publication year - 2008

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/590006

Subject(s) - mannan binding lectin , odds ratio , medicine , confidence interval , sepsis , streptococcus pneumoniae , bacteremia , intensive care unit , immunology , gastroenterology , lectin , antibiotics , biology , microbiology and biotechnology

Previous studies have shown associations between low mannose-binding lectin (MBL) level or variant MBL2 genotype and sepsis susceptibility. However, MBL deficiency has not been rigorously defined, and associations with sepsis outcomes have not been subjected to multivariable analysis.

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