Prevention of Symptomatic Seasonal Influenza in 2005–2006 by Inactivated and Live Attenuated Vaccines
Author(s) -
Suzanne E. Ohmit,
John C. Victor,
Esther Teich,
Rachel Truscon,
Judy R. Rotthoff,
Duane W. Newton,
Susan L. Campbell,
Matthew L. Boulton,
Arnold S. Monto
Publication year - 2008
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/589885
Subject(s) - inactivated vaccine , attenuated vaccine , live attenuated influenza vaccine , virology , medicine , influenza vaccine , influenza a virus , virus , titer , vaccine efficacy , placebo , vaccination , orthomyxoviridae , immunology , biology , virulence , biochemistry , alternative medicine , pathology , gene
The efficacy of influenza vaccines may vary annually. In 2004-2005, when antigenically drifted viruses were circulating, a randomized, placebo-controlled trial involving healthy adults showed that inactivated vaccine appeared to be efficacious, whereas live attenuated vaccine appeared to be less so.
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