Human Genetic Resistance toOnchocerca volvulus:Evidence for Linkage to Chromosome 2p from an Autosome‐Wide Scan
Author(s) -
Christian Timmann,
Esther van der Kamp,
André Kleensang,
Inke R. König,
Thorsten Thye,
Dietrich W. Büttner,
Christoph Hamelmann,
Yeboah Marfo,
Maren Vens,
Norbert W. Brattig,
Andreas Ziegler,
Rolf D. Horstmann
Publication year - 2008
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/589720
Subject(s) - biology , onchocerca volvulus , microsatellite , genetic linkage , genetics , autosome , chromosome , genetic marker , linkage (software) , onchocerciasis , gene , immunology , allele
Human infections with the tissue nematode Onchocerca volvulus show strong interindividual variation in intensity, which cannot be explained by differences in exposure alone. Several lines of evidence suggest a relevant influence of human genetics.
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