Hepatitis C Virus (HCV)–Specific Immune Responses of Long‐Term Injection Drug Users Frequently Exposed to HCV
Author(s) -
Eishiro Mizukoshi,
Christoph Eisenbach,
Brian R. Edlin,
Kimberly P. Newton,
Sukanya Raghuraman,
Christina WeilerNormann,
Leslie H. Tobler,
Michael P. Busch,
Mary Carrington,
Jane A. McKeating,
Thomas R. OʼBrien,
Barbara Rehermann
Publication year - 2008
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/589510
Subject(s) - elispot , hepatitis c virus , immunology , medicine , virology , antibody , hepatitis c , hepacivirus , immune system , virus , t cell
Injection drug users (IDUs) who successfully clear hepatitis C virus (HCV) have a reduced risk of developing chronic reinfection, despite their continuing exposure to the virus. To identify immunological correlates for this apparent protection, we studied HCV-specific immune responses in long-term IDUs (duration, >10 years).
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