Outcomes of a Standardized Triple‐Drug Regimen for the Treatment of Nontuberculous Mycobacterial Pulmonary Infection | Zendy

M Murray | Zendy; Ian F. Laurenson | Zendy; Adam T. Hill | Zendy

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Outcomes of a Standardized Triple‐Drug Regimen for the Treatment of Nontuberculous Mycobacterial Pulmonary Infection

Author(s) -

M Murray,

Ian F. Laurenson,

Adam T. Hill

Publication year - 2008

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/589250

Subject(s) - medicine , sputum , sputum culture , nontuberculous mycobacteria , regimen , culture conversion , drug , pulmonary infection , immunology , mycobacterium , tuberculosis , pathology , pharmacology

The treatment of fibrocavitatory pulmonary infection due to Mycobacterium avium complex and Mycobacterium malmoense poses a challenge. This study assessed microbial, inflammatory, radiographic, and clinical outcomes for a standardized 24-month triple-drug regime. Following treatment completion, all patients had fewer symptoms, experienced a reduction in systemic inflammation, and had negative sputum mycobacterial culture results.

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