Prospective Study of Serologic Tests for Lyme Disease | Zendy

Allen C. Steere | Zendy; Gail McHugh | Zendy; Nitin Damle | Zendy; Vijay K. Sikand | Zendy

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Prospective Study of Serologic Tests for Lyme Disease

Author(s) -

Allen C. Steere,

Gail McHugh,

Nitin Damle,

Vijay K. Sikand

Publication year - 2008

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/589242

Subject(s) - medicine , lyme disease , serology , prospective cohort study , borrelia burgdorferi , virology , immunology , antibody

Tests to determine serum antibody levels-the 2-tier sonicate immunoglobulin M (IgM) and immunoglobulin G (IgG) enzyme-linked immunosorbent assay (ELISA) and Western blot method or the IgG of the variable major protein-like sequence-expressed (VlsE) sixth invariant region (C6) peptide ELISA method-are the major tests available for support of the diagnosis of Lyme disease. However, these tests have not been assessed prospectively.

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