Valganciclovir for Suppression of Human Herpesvirus–8 Replication: A Randomized, Double‐Blind, Placebo‐Controlled, Crossover Trial | Zendy

Corey Casper | Zendy; Elizabeth M. Krantz | Zendy; Lawrence Corey | Zendy; Steven R. Kuntz | Zendy; Jie Wang | Zendy; Stacy Selke | Zendy; Shan Hamilton | Zendy; MeeiLi Huang | Zendy; Anna Wald | Zendy

Open Access

Valganciclovir for Suppression of Human Herpesvirus–8 Replication: A Randomized, Double‐Blind, Placebo‐Controlled, Crossover Trial

Author(s) -

Corey Casper,

Elizabeth M. Krantz,

Lawrence Corey,

Steven R. Kuntz,

Jie Wang,

Stacy Selke,

Shan Hamilton,

MeeiLi Huang,

Anna Wald

Publication year - 2008

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/588820

Subject(s) - crossover study , valganciclovir , placebo , double blind , replication (statistics) , randomized controlled trial , medicine , crossover , human herpesvirus , virology , human cytomegalovirus , virus , pathology , ganciclovir , computer science , alternative medicine , artificial intelligence

Human herpesvirus-8 (HHV-8) replication is critical in the induction and maintenance of Kaposi sarcoma, primary effusion lymphoma, and some cases of Castleman disease. In vitro and observational studies suggest that ganciclovir inhibits HHV-8 replication, but no randomized clinical trials have been conducted.

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