Open AccessIndependent Effects of Genetic Variations in Mannose‐Binding Lectin Influence the Course of HIV Disease: The Advantage of Heterozygosity for Coding Mutations
Author(s) -
Gabriel Catano,
Brian K. Agan,
Hemant Kulkarni,
Vanessa Telles,
Vincent C. Marconi,
Matthew J. Dolan,
Sunil K. Ahuja
Publication year - 2008
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/588712
Subject(s) - mannan binding lectin , loss of heterozygosity , lectin , biology , genetics , mannose , mutation , immunology , gene , allele , biochemistry
The in vivo impact of mannose-binding lectin (MBL), a molecule involved in innate immunity, on the pathogenesis of human immunodeficiency virus (HIV)-1 infection and AIDS is unknown.
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