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Risk Factors and Mortality Associated with Default from Multidrug‐Resistant Tuberculosis Treatment
Author(s) -
Molly F. Franke,
Sasha C. Appleton,
Jaime Bayona,
Fernando Arteaga,
Eda Palacios,
Karim Llaro,
Sonya Shin,
Mercedes C. Becerra,
Megan Murray,
Carole D. Mitnick
Publication year - 2008
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/588292
Subject(s) - medicine , hazard ratio , interquartile range , confidence interval , culture conversion , default , tuberculosis , sputum , pathology , finance , economics
Completing treatment for multidrug-resistant (MDR) tuberculosis (TB) may be more challenging than completing first-line TB therapy, especially in resource-poor settings. The objectives of this study were to (1) identify risk factors for default from MDR TB therapy (defined as prolonged treatment interruption), (2) quantify mortality among patients who default from treatment, and (3) identify risk factors for death after default from treatment.

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