Molecular Markers of Resistance to Sulfadoxine‐Pyrimethamine during Intermittent Preventive Treatment for Malaria in Mozambican Infants | Zendy

Alfredo Mayor | Zendy; Elisa SerraCasas | Zendy; Sergi Sanz | Zendy; John J. Aponte | Zendy; Eusébio Macete | Zendy; Inácio Mandomando | Zendy; Laura Puyol | Zendy; Pedro Berzosa | Zendy; Carlota Dobaño | Zendy; Pedro Aíde | Zendy; Jahit Sacarlal | Zendy; Agustín Benito | Zendy; Pedro L. Alonso | Zendy; Clara Menéndez | Zendy

Open Access

Molecular Markers of Resistance to Sulfadoxine‐Pyrimethamine during Intermittent Preventive Treatment for Malaria in Mozambican Infants

Author(s) -

Alfredo Mayor,

Elisa SerraCasas,

Sergi Sanz,

John J. Aponte,

Eusébio Macete,

Inácio Mandomando,

Laura Puyol,

Pedro Berzosa,

Carlota Dobaño,

Pedro Aíde,

Jahit Sacarlal,

Agustín Benito,

Pedro L. Alonso,

Clara Menéndez

Publication year - 2008

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/588144

Subject(s) - sulfadoxine , sulfadoxine/pyrimethamine , dhps , pyrimethamine , malaria , placebo , odds ratio , medicine , drug resistance , population , pediatrics , plasmodium falciparum , immunology , biology , environmental health , microbiology and biotechnology , pathology , alternative medicine

Intermittent preventive treatment in infants (IPTi) with sulfadoxine-pyrimethamine (SP) is a potential malaria control strategy. There is concern about the impact that increasing in vivo resistance to SP has on the efficacy of IPTi, as well as about the potential contribution of IPTi to increases in resistance.

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