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Invasive Pulmonary Infection Due toTrichoderma longibrachiatumMimicking Invasive Aspergillosis in a Neutropenic Patient Successfully Treated with Voriconazole Combined with Caspofungin
Author(s) -
Alexandre Alanio,
Benoît Brethon,
M. Feuilhade de Chauvin,
É. de Kerviler,
Thierry Leblanc,
Christophe Lacroix,
André Baruchel,
Jean Ménotti
Publication year - 2008
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/587750
Subject(s) - voriconazole , caspofungin , medicine , aspergillosis , trichoderma , neutropenia , microbiology and biotechnology , dermatology , immunology , antifungal , chemotherapy , biology , horticulture
Trichoderma longibrachiatum, a filamentous fungus, was recently described as an emerging pathogen in immunocompromised patients. Here, we report the first case, to our knowledge, of isolated invasive lung infection by T. longibrachiatum in a patient with hematologic malignancy. The infection mimicked invasive pulmonary aspergillosis and was successfully treated with a combination of voriconazole and caspofungin.

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