Clinical and Virological Characteristics of 15 Patients with Chronic Active Epstein‐Barr Virus Infection Treated with Hematopoietic Stem Cell Transplantation
Author(s) -
Kensei Gotoh,
Yoshinori Ito,
Yukiko ShibataWatanabe,
Junichi Kawada,
Yoshiyuki Takahashi,
Hiroshi Yagasaki,
Seiji Kojima,
Yukihiro Nishiyama,
Hiroshi Kimura
Publication year - 2008
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/587671
Subject(s) - medicine , hematopoietic stem cell transplantation , viral load , mononucleosis , transplantation , virus , immunology , gastroenterology
Chronic active Epstein-Barr virus (EBV) infection is characterized by recurrent infectious mononucleosis-like symptoms, and infected patients have high viral loads in their peripheral blood. Standard therapy for the disease has not yet been established. Recently, hematopoietic stem cell transplantation (HSCT) has been introduced and has the potential to become a standard treatment, although guidelines for HSCT to treat chronic active EBV infection have not yet been proposed.
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